Aerinaze – Use | Dose | Side Effects

Aerinaze is a medicine that contains two active substances: pseudoephedrine (120 mg) and desloratadine (2.5 mg). It belongs to the group of medicines called systemic nasal decongestants. It is used to relieve symptoms of an allergic rhinitis (also known as hay fever) accompanied by stuffy nose (congestion).


Aerinaze should be avoided in following conditions:

  • In patients with heart diseases, such as:
    • high blood pressure (hypertension),
    • rapid heartbeat (tachycardia),
    • arrhythmia (irregular heartbeat),
    • cardiac insufficiency, and others. This medicine contains pseudoephedrine, therefore it may worsen symptoms in such patients.
  • Patients who have had heart attack.
  • In patients with urinary retention (inability to urinate).
  • In patients with hyperthyroidism (overactive thyroid).
  • Patients who suffered a stroke.
  • In patients with glaucoma (high eye pressure).
  • In patients with bladder disorders.
  • In patients who are allergic to any of its active substances (pseudoephedrine and desloratadine)

This medicine contains pseudoephedrine (a sympathomimetic, like adrenalin-epinephrine), and because of that, this medicine may cause rapid heartbeat (tachycardia), irregular heartbeat (arrhythmia) or high blood pressure (hypertension). If you are experiencing any of abovementioned symptoms, contact your doctor immediately.

If you are experiencing nausea, headache or dizziness, contact your doctor immediately.

Because it contains pseudoephedrine, this medicine may be abused. If you use it long term or take high doses of this medicine, it may cause serious side effects.

This medicine may induce positive results in anti-doping tests.

Use of Aerinaze during pregnancy and breastfeeding

Use of this medicine during pregnancy and breastfeeding is not recommended, because there is not enough data on its safety.


It passes into breast milk, therefore breastfeeding should be avoided while using this medicine.

How to use

The usual dose is one Aerinaze tablet twice a day. Do not take this medicine for more than 10 days! The duration of treatment should be kept as short as possible.

It should be used with extra precautions in patients above the age of 65, because elderly patients are at greater risk.

It can be taken with or without food, because food intake do not influence the effectiveness of Aerinaze.

Swallow the tablet whole, with a glass of water. Do not crush or chew the tablet, because this can affect Aerinaze effectiveness.

It should be avoided in patients under the age of 12.

Use with other medicines (Interactions)

Aerinaze should be avoided in combination with following medicines:

  • Medicines used to treat high blood pressure, such as: methyldopa.
  • Medicines used to treat cardiac insufficiency (heart failure), such as: digoxin.
  • Medicines used to treat migraine, such as:
    • dihydroergotamine,
    • ergotamine and others.
  • Bromocriptine, medicine used to treat Parkinson’s disease and symptoms of hyperprolactinemia (high levels of prolactin in the body).
  • Medicines used to treat depression (antidepressants)
  • Medicines used to treat various mental illnesses (antipsychotics).
  • Antacids, medicines used to relieve symptoms of heartburn and ulcers.

Tell your doctor about all medications and herbal products you are using.

Side effects

Aerinaze may cause the following side effects:

  1. nausea,
  2. vomiting,
  3. constipation,
  4. dyspepsia,
  5. headaches,
  6. dizziness,
  7. insomnia,
  8. nervousness,
  9. anxiety,
  10. rapid heartbeat (tachycardia),
  11. arrhythmia (irregular heartbeat),
  12. high blood pressure (hypertension),
  13. dry mouth,
  14. muscle pain,
  15. difficulty urinating,
  16. painful urination,
  17. sinusitis (inflammation of the sinuses),
  18. sore throat,
  19. nosebleeds,
  20. allergy and others.

Tell your doctor if you are experiencing any side effects.


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