Berodual – Use | Dose | Side Effects

Berodual is a medicine that contains the two active substances: ipratropium bromide and fenoterol. It belongs to a group of medicines called bronchodilators. It is used for the treatment or prevention of bronchospasm (tightening of the airways going into the lungs) in asthma and chronic obstructive pulmonary disease.


It should be avoided in patients allergic to any of the active substances (ipratropium bromide and fenoterol). If you are experiencing symptoms of an allergy, such as:

  1. swelling of the face,
  2. swelling of the tongue,
  3. shortness of breath,

discontinue use and call your doctor.

This medicine should be avoided in patients with rapid heart rate (tachycardia) or hypertrophic obstructive cardiomyopathy (inherited disease of the heart muscle). Tell your doctor if you have any heart disease before you start using this medicine.

Berodual should be used only with extra precautions in the following conditions:

  • Pheochromocytoma (tumor of the adrenal gland)
  • Hyperthyroidism (overactive thyroid gland)
  • In patients who have had a heart attack
  • Diabetes
  • In patients who have low potassium levels or taking medications that may cause potassium loss. Low potassium levels in the blood can cause serious arrhythmias (irregular heartbeat)
  • In patients with glaucoma (increased eye pressure). Take care to avoid getting Berodual spray in your eyes, because it can cause eye damage.

It should be used only if necessary. Avoid iIts frequent use, because it may be a sign that the disease is more difficult to control.

Athletes need to be aware that this medicine may affect the results of the doping test.


Use during pregnancy and breastfeeding

Berodual can be used during pregnancy only if the benefit to the mother outweighs the risk to the child.

This medicine passes into breast milk therefore breastfeeding should be avoided while using this medicine.

Berodual Use and Dose

In an asthma attack, the usual dose is 20 drops (1 ml). In severe cases it can be used up to 4 ml (80 drops) of Berodual solution.

In children aged 6-12 years, usual dose is 10-20 drops (0.5 ml-1 ml).

Berodual dosage forms include: spray and solution. Solution should be used via suitable inhalers. Do not swallow Berodual solution!

This medicine should be mixed with saline (0.9% NaCl) to a volume of 4 ml. Thus prepared solution should be inhaled until all the liquid has been emptied.

Use with other medicines (Interactions)

Berodual should be avoided in combination with the following medicines:

  • Medicines used in the treatment of heart disease, the so-called beta-blockers, such as:
  • Theophylline, a medicine used in the treatment of asthma.
  • Medicines that may cause potassium loss, such as:
    • hydrochlorothiazide,
    • furosemide (Lasix),
    • torasemide, and others. The concomitant use of these medicines with Berodual, can cause low potassium levels in the blood and lead to serious cardiac arrhythmias (irregular heartbeat).

Tell your doctor about all medications and herbal products you are taking.

Side effects

Berodual may cause the following side effects:

  1. headache,
  2. dizziness,
  3. increased blood pressure (hypertension),
  4. dry mouth,
  5. tremor,
  6. low potassium levels in the blood,
  7. high eye pressure (glaucoma),
  8. rapid heart rate (tachycardia),
  9. cough,
  10. nausea,
  11. vomiting,
  12. muscle pain,
  13. difficulty urinating,
  14. allergy and others.

Tell your doctor if you are experiencing any side effects.


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