Betaferon injection for multiple sclerosis

Betaferon injection contains an active substance called interferon beta-1b. It belongs to a group of medicines called cytokines and immunomodulators. It is used to treat multiple sclerosis.


  • It should be avoided in patients with severe liver damage. It may cause serious liver damage, and it is necessary to immediately contact your doctor if you are experiencing any symptoms of liver damage, such as:
    • loss of appetite,
    • dark urine,
    • vomiting,
    • stomach pain,
    • swelling in the stomach,
    • jaundice (yellowing of your skin and eyes).
  • It should be avoided during pregnancy and breastfeeding.
  • It must not be used in patients allergic to interferon or other similar substances. If you are experiencing symptoms of an allergy, such as:
    • redness,
    • itching,
    • swelling,
    • breathing difficulty, contact your doctor immediately.
  • It is not recommended for use in patients suffering from depression. It can cause suicidal ideation. Immediately contact your doctor if you are experiencing this symptom.
  • It should be used only with extra precautions in patients with immune system disorders, as well as in patients with anemia, thrombocytopenia (low blood platelet count) or leukopenia (low white blood cell count).
  • Betaferon must be used with extra precautions in patients with cardiovascular disorders.

Use of Betaferon during pregnancy and breasfeeding

It should be used during pregnancy only if the benefit to the mother outweighs the risk to the child. Avoid breastfeeding while using this injection.

Betaferon injection use and dosage

  • It should be administered as an injection and may be applied only by trained medical personnel.
  • Usual initial dose of is Betaferon 62.5 micrograms every other day. The dosage should be gradually increased until reaching dose of 250 micrograms.
  • It should be avoided in patients under the age of 12.
  • Duration of treatment is usually more years, depending on the patient’s condition.
  • Your doctor will determine for how long you need to use Betaferon injections.

Use with other medicines (Interactions)

There are no known published studies on interactions with other drugs.

Caution should be exercised when this injection is used along with drugs used to treat epilepsy and warfarin (Farin), which is used to treat blood clotting disorders.

Betaferon side effects

It may cause the following side effects:

  1. anemia,
  2. thrombocytopenia (low blood platelet count),
  3. leukopenia (low white blood cells),
  4. decreased immune system,
  5. flu-like symptoms (fever, cough, sore throat),
  6. pain at the site of injection,
  7. redness,
  8. swelling at the site of injection,
  9. necrosis at the site of injections,
  10. headache,
  11. dizziness,
  12. insomnia,
  13. nausea,
  14. vomiting,
  15. abdominal pain,
  16. liver damage that accompanies with jaundice,
  17. muscle pain,
  18. trouble urinating,
  19. high blood pressure (hypertension),
  20. mood changes,
  21. suicidal thoughts ,
  22. allergy and others.

Tell your doctor if you are experiencing any side effects.


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