Bridion – precautions | interactions | side effects

Bridion is a drug that contains an active substance called sugammadex. It belongs to a group of medicines that block muscle relaxants (drugs that are administered to relax muscles), which speeds up recovery after surgery. Muscle relaxants are used to relax muscles during the surgery.

Since these drugs are relaxing all muscles, they also relax muscles in your airways, and because of that, patient breathes with the help of the machines during the surgery. When surgery is finished, This medicament may be used to speed up the recovery process and to eliminate the effect of muscle relaxants.

Bridion is usually used at the end of the surgery to block the effect of muscle relaxants (rocuronium, vecuronium) and to speed up recovery and bring back normal breathing (without machines).


It should be avoided in patients allergic to the active substance sugammadex. It must be used with extra precautions in patients with liver disorders, kidney disorders, heart disease, or in patients with swelling.

Tell your doctor if you have any of these disorders.

Use of Bridion during pregnancy and breastfeeding

Bridion can be used during pregnancy and breastfeeding.

How to use Bridion

The usual dose is Bridion 2-4 mg per kilogram of body weight.


Example: If your body weight is 80 kg, and your anesthesiologist determine dose of 2 mg per kg, then the dose will be: 80 x 2 = 160 mg of Bridion.

The dose may be higher (4 mg per kg or 80 x 4 = 320 mg), if your anesthetist determined so.

Bridion should be used only after surgery and should be administered by trained medical staff (usually an anesthesiologist). It can only be given intravenously.

Use with other medicines (Interactions)

There are no much interactions with this drug. The only noteworthy interaction is the interaction with oral contraceptives (medicines used to prevent pregnancy). Bridion drug can reduce the effect of oral contraceptives, and it is necessary to inform the patient to use an additional protection during sexual intercourse.

Tell your doctor about all medications and herbal products you are using.

Side effects

Bridion tablets may cause the following side effects:

  • the feeling of a bad taste in the mouth,
  • muscle weakness,
  • cough,
  • allergy and others.

Contact your doctor if you notice any of the side effects.


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