Dysport – Use | Dose | Side Effects

Dysport is a medicine that contains an active substance called clostridium botulinum toxin type A. This medicine works by blocking the calcium ion- induced processes in nerve endings. Dysport is used in the treatment of the following diseases:

  1. Cervical dystonia (involuntary spasm of the neck muscles producing twisting of the neck and an unnatural position of the head)
  2. Blepharospasm (rapid and uncontrolled contractions or twitching of the eyelids, causing patients have inreasing difficulty keeping their eyes open)
  3. Spasticity after a stroke (involuntary movements, overactive reflexes, pain in the arms)
  4. Hemifacial spasm (uncontrollable, involuntary movements of the face muscles)
  5. In patients with spastic feet due to infantile paralysis
  6. In patients with excessive sweating in the armpit area, that interfere with your everyday life

Dysport should be administered only by a trained doctor, even when it is used for cosmetic purposes.


Dysport should be avoided in patients allergic to the active substance of this medicine.

Dysport should be administered only by trained doctors. The toxin contained in this medicine may spread to other areas of the body, causing adverse effects. Most common adverse effect is muscle weakness. The risk of side effects can be reduced by injecting the lowest dose possible.

It should be noted that deaths have been reported, although very rarely. The risk of death is higher in patients who have breathing problems. In these patients this medicine should be used only if benefits outweighs the risks.

Dysport should be used only with extra precautions in patients with myasthenia gravis (neuromuscular disease characterized by muscle weakness).

It must be used with extra precautions in the following conditions:

  • In patients who have a prolonged bleeding time
  • Patients who have inflammation at the injection site
  • In patients who have an infection

Use of Dysport during pregnancy and breastfeeding

Dysport should be used during pregnancy only if the benefit to the mother outweighs the risk to the child.

It is not known whether this medicine passes into breast milk, but it is recommended to avoid breastfeeding while using this medicine.

How to use

Dysport is diluted with saline (0.9% NaCl). It can be administered via intradermal, subcutaneous, or intramuscular route, depending on condition.

It can be administered only by specialized doctors who have undergone appropriate training.

Use with other medicines (Interactions)

Dysport should be avoided in combination with the following medicines:

  • Medicines that may affect neuromuscular function, such as:
    • tubocurarine,
    • pancuronium,
    • venkuronijum,
    • neostigmine,
    • pyridostigmine,
    • bromazepam,
    • lorazepam,
    • nitrazepam,
    • midazolam and others.

Tell your doctor about all medications and herbal products you are taking.

Side effects

Dysport may cause the following side effects:

  1. muscle pain,
  2. muscle weakness,
  3. general weakness,
  4. flu-like symptoms (cough, fever, sore throat),
  5. difficulty swallowing,
  6. difficulty breathing,
  7. urinary incontinence,
  8. diarrhea,
  9. dry mouth,
  10. allergy and others.

Tell your doctor if you are experiencing any side effects.


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