Tolterodine – Use | Dosage and Side Effects
Tolterodine is a medicine that belongs to a group of medicines called urinary antispasmodics. It is used to treat urinary incontinence (the loss of bladder control), which can affect the daily life of patient. This problem can be embarrassing, due to the urine leakage may happen even when you cough, sneeze, laugh or jump.
It should be avoided in patients allergic to this medicine and other similar medicines. If you are experiencing symptoms of an allergy, such as:
- swelling of the face,
- swelling of the tongue,
- difficulty breathing, contact your doctor.
Tolterodine should be avoided in patients with myasthenia gravis (severe neuromuscular disease), because it can worsen symptoms in such patients.
It should be avoided in patients with urinary retention (inability to urinate).
It should be avoided in patients with glaucoma (increased eye pressure).
Tolterodine should be used with extra precautions in the following conditions:
- In patients with liver or kidney damage
- Gastrointestinal tract damage
- In patients with bladder damage
- Patients with neuropathy
- In patients with heart rhythm disorders (arrhythmia)
- In patients with heart diseases
- Patients who have low levels of potassium, magnesium or calcium in the blood
- In patients who take medicines used to treat arrhythmia, known as antiarrhythmics
Use during pregnancy and breastfeeding
Tolterodine can be used during pregnancy only if the benefit to the mother outweighs the risk to the child. Talk to your doctor about the benefits and risks of using this medicine during pregnancy.
It should not be used during breastfeeding.
Use and Dosage
Tolterodine should be used at a dose of 2 mg, two times per day. The treatment should last for a few months (2 to 3 months). After three months, your doctor may advice that you continue to take Tolterodine.
Dose may be reduced in patients with liver or kidney diseases (1 mg two times per day).
It is not recommended use in patients under the age of 18.
It should not be used in combination with alcoholic beverages.
Swallow the tablet whole with a glass of water.
Use with other medicines (Interactions)
Tolterodine should be avoided in combination with the following medicines:
- Medicines used to treat arrhythmia (antiarrhythmics)
- Medicines used in the treatment of bacterial infections, such as:
- azithromycin, and others. These medicines can increase level of Tolterodine in the blood, increasing the risk of side effects.
- Medicines used in the treatment of fungal infections, such as:
- fluconazole, and others. These medicines can increase level of Tolterodine in the blood, increasing the risk of side effects.
- Metoclopramide (Klometol), a medicine used in the treatment of nausea. Tolterodine can reduce the effect of this medicine.
- Pilocarpine, a medicine used to treat glaucoma (in the form of eye drops). This medicine can block the effect of Tolterodine.
Tell your doctor about all medications and herbal products you are taking.
This medicine may cause the following side effects:
- abdominal pain,
- acid reflux dry mouth,
- impaired vision,
- increased body weight,
- allergy and others.
Tell your doctor if you are experiencing any side effects.