Aerius - Use | Dose | Side Effects

This article was medically reviewed by M.Pharm, Marko Tanaskovic on Thu, 27 Dec 2018. To read more about an author, click here.

Aerius is a medicine that contains an active substance called desloratadine. It belongs to a group of medicines called antihistamines. It works by blocking histamine H1 receptors, thereby block the action of histamine at the H1 receptors, so that histamine messages are not received, thus helping relieve allergy symptoms. It is used to relieve symptoms of an allergic rhinitis and urticaria (hives). Allergic rhinitis is a condition that is manifested by symptoms, such as:

  1. runny nose,
  2. frequent sneezing and stuffy nose.


It should be avoided in patients allergic to the active substance, desloratadine or other similar medicines. Although this medicine is used to relieve allergy symptoms, sometimes the allergic reaction is caused by the medicine itself. Consult your doctor if you are experiencing symptoms of an allergy, such as:

  • swelling of the face,
  • swelling of the tongue,
  • shortness of breath and others.

This medicine should be used with extra precautions in patients with renal impairment, because this medicine is excreted mainly via the kidneys.

Aerius tablets should be avoided in patients under the age of 12, because the safety of Aerius tablets have not been established for patients under the age of 12.

Use during pregnancy and breastfeeding

It should be used during pregnancy only if the benefit to the mother outweighs the risk to the child.

This medicine passes into breast milk. Breastfeeding should be avoided while using this medicine.

Use and Dose

Dosage forms include: Aerius 5 mg tablets and Aerius syrup.

Aerius 5 mg should be used once a day, regardless of the food, because the food does not affect this medicine. It belongs to nonsedating antihistamines (most other antiallergic medicines are sedating), so you can take it at any time of day, either before or after a meal. Aerius tablets can be used only in patients above the age of 12.

Aerius syrup can be used in patients under the age of 12.


Age Dose
Children aged 1-5 years 2.5 ml of Aerius syrup, once a day
Children aged 6-11 years 5 ml of Aerius syrup, once a day
Patients above the age of 12 10 ml of Aerius syrup, once a day

It can be taken for long periods of time, while symptoms persist. Aerius therapy should be discontinued when symptoms subside. If your allergy symptoms come back again, you may take this medicine again.

Use with other medicines (Interactions)

Aerius should be avoided in combination with the following medicines:

  • Amiodarone, a medicine used in the treatment of arrhythmias (irregular heartbeat). Concomitant use of this medicine with Aerius, increases the risk of arrhythmia.
  • Antibiotics, medicines used in the treatment of bacterial infections, such as:
    • azithromycin,
    • clarithromycin,
    • erythromycin and others. These medicines may increase the level of Aerius in the blood, increasing the risk of side effects.

Tell your doctor about all medications and herbal products you are taking.

Aerius side effects

Aerius may cause the following side effects:

  1. dizziness,
  2. somnolence (sleepiness, drowsiness),
  3. nausea,
  4. vomiting,
  5. muscle pain,
  6. hallucinations,
  7. insomnia,
  8. seizures,
  9. allergy and others.

If you are experiencing dizziness or somnolence, avoid driving a motor vehicle or operating machinery.

Tell your doctor if you are experiencing any side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.