Amoxil - Use | Overdose | Side Effects

This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.

Amoxil (Amoxicillin) is medicine that belongs to the group of medicines called penicillins (antibiotics). Amoxil causes damage to bacterial cell wall which leads to their destruction. This medicine is used to treat bacterial infections caused by susceptible microorganisms:

  • Upper respiratory tract infections (pharyngitis and laryngitis);
  • Inflammation of the middle ear (otitis media);
  • Acute and chronic bronchitis;
  • Chronic bronchial inflammation;
  • Pneumonia;
  • Bladder, urethra and kidney infections;
  • Urinary tract infections during pregnancy;
  • Gynecological infections;
  • Gonorrhea;
  • Inflammation of the peritoneum (peritonitis);
  • Intra-abdominal infections;
  • Bacterial infection of the blood (bacteremia);
  • Endocarditis (infection of heart's valves);
  • Typhoid fever;
  • Skin and soft tissue infections ;
  • Infections in teeth and gums;
  • Helicobacter pylori infection;
  • Antibiotic prophylaxis for dental patients at risk for infections


Amoxil should be avoided in following conditions:

  • In patients allergic to Amoxil or any other similar medicines, such as: penicillins or cephalosporins.
  • In patients with infectious mononucleosis (a viral infection) and / or lymphatic leukemia.

Amoxil should be used only with extra precautions in following conditions:

  • In patients with urinary problems
  • In patients with kidney damage. Amoxil elimination is reduced in patients with impaired renal function. Dose reduction may therefore be required when prescribing Amoxil for these patients.

Use with other medicines (Interactions)

Amoxil should be avoided in combination with following medicines:

  • Medicines used to treat gout, such as: probenecid and allopurinol. Concomitant use of Amoxil with probenecid may increase concentration of Amoxil in the blood and increases the risk of side effects. Concomitant use with allopurinol increases the risk of allergic skin reactions;
  • Oral contraceptives (birth control pills). Concomitant use of Amoxil with these medicines, reduces the risk of birth control pills;
  • Medicines that prevent the blood from clotting (anticoagulants).

Use of Amoxil during pregnancy and breastfeeding

Amoxil should be used during pregnancy only if the benefit to the mother outweighs the risk to the child. FDA category: B. Animal studies have shown no adverse effects for fetus, but there are not studies in humans.

Amoxil passes into breast milk, therefore breastfeeding should be avoided while using this medicine.

Medicines use

Dose depends on the severity of the infections. Usual dose for adults is 500 mg three times a day.

  • Swallow this medicine whole with a glass of water.
  • Maximum daily dose is 6 g.
  • Do not use this medicine for more than 2 weeks. Call your doctor if your symptoms get worse or do not improve after 2 weeks of treatment.
  • If you take this medicine over a long period of time, fungal infections may develop, in which case you should contact your doctor.


Symptoms of an overdose include:

  • Nausea
  • Diarrhea
  • Crystals in the urine.

Side effects

Common side effects (less than 1 in 10 people are affected):

  • skin rash;
  • nausea;
  • diarrhea.

Occasional side effects (less than 1 in 100 people are affected):

  • vomiting;
  • allergic skin reactions.

Very rare side effects (less than 1 in 10 000 people are affected):

  • Allergic reaction (swelling of the face, swelling of the throat abd difficulty breathing)
  • Renal impairment;
  • Convulsions (seizures);
  • Dizziness;
  • Hyperactivity;
  • Crystals in the urine. Drinking plenty of fluids may help you prevent crystal formation.
  • Tooth discoloration;
  • Black hairy tongue;
  • Low white blood cell count
  • Low blood platelet count;
  • Prolonged prothrombin time.

Call your doctor if you are experiencing any side effects.

Brand names: Amoxicillin, Moxatag, Trimox and Wymox.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.

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