Anazol - drug use | side effects and more

This article was medically reviewed by M.Pharm, Marko Tanaskovic on Thu, 27 Dec 2018. To read more about an author, click here.

Anazol is a drug that contains an active substance called anostrozol and belongs to a group of medicines called aromatase inhibitors. This medicine blocks enzyme aromatase, thus reducing the production of estrogens (female sex hormone), therefore it can slow down the growth of some breast cancer tumors.

It is used in the treatment of estrogen-receptor-positive breast cancer (also called hormone dependent tumor) in postmenopausal women. Anazol is effective only for the treatment of breast cancers which are hormone-dependent.


Anazol as a hormonal preparation may increase the risk of thrombus formation in blood and therefore may cause heart attack or stroke. Tell your doctor if you have or have ever had circulation problems or if someone in your family has similar problems.

  • It must not be used in women have not gone through menopause!
  • It should be avoided in patients allergic to the active substance (anastrozole) or other similar drugs.
  • Also should be avoided in patients with kidney or liver disorders.
  • Anazol should be avoided in combination with other estrogen preparations (keep this in mind if you are using an oral contraceptive pill).
  • It can reduce bone density therefore it is necessary to periodically measure the density of your bones. Probably you will need to take some medications to slow or stop bone loss, thereby lowering the risk of bone fractures.
  • Anazol passes into body fluids (urine, feces, vomit), therefore health care workers need to wear protective gloves and masks to avoid direct contact with body fluids.

Use of Anazol during pregnancy and breastfeeding

It can be used during pregnancy only if the benefit to the mother outweighs the risk to the child. Anazol can cause side effects on fetus! Avoid breastfeeding while using this drug.

Anazol use

Anazol should be taken once a day with a glass of water, with or without food, since that food does not affect the efficacy of this drug.

Use with other medicines (Interactions)

Anazol should be avoided with the following medications:

  • Estrogen preparations (birth control pills, various creams, ointments and other products that contain estrogen derivatives).
  • Tamoxifen (Nolvadex), used in the treatment of breast cancer.

Tell your doctor about all medications and herbal products you are taking.

Anazol side effects

It may cause the following side effects:

  1. hot flushes (occurs very often),
  2. nausea,
  3. vomiting,
  4. headache,
  5. diarrhea,
  6. alopecia (hair loss),
  7. lethargy (a state of tiredness or lack of energy),
  8. blurred vision,
  9. hearing impairment,
  10. heart disorders,
  11. increased blood pressure,
  12. nervousness,
  13. vaginal dryness,
  14. vaginal bleeding,
  15. loss of appetite,
  16. allergy and others.

Tell your doctor if you are experiencing any side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.