Andriol - Use | Dose | Side Effects

Andriol is a drug that contains an active substance called testosterone undecanoate.

It belongs to the hormonal preparations.

Testosterone is a male sex hormone and it is responsible for the development and maintenance of male sexual characteristics.

This medicine is used to treat certain diseases and conditions associated with low levels of testosterone (hypogonadism). It is also used after gender reassignment surgery female to male.


This drug should be avoided in the following conditions:

  • If you are allergic to testosterone.
  • If you have androgen-dependent prostate cancer or androgen-dependent breast cancer
  • Have too much calcium in your blood (hypercalcemia)
  • During pregnancy and breastfeeding

It must to be used with caution in patients with

  1. heart disorders,
  2. diabetes,
  3. blood clotting disorders,
  4. prostate problems as well as in the patients with liver or kidney disorders.

Andriol should be used with extreme caution in patients with epilepsy.

It may worsen the cancer in a patient with breast cancer or prostate cancer, and therefore should be avoided in such patients.

This medicament may cause serious pulmonary embolism, which can be life threatening. If you have difficulties breathing, contact your doctor immediately.

Andriol may cause an allergy which can be life threatening! Tell your doctor if you are experiencing symptoms of an allergy such as:

  1. rash,
  2. itching,
  3. redness,
  4. swelling,
  5. trouble breathing.

It should be used only for the hypogonadism treatment or as hormone replacement therapy which means that you are using synthetic testosterone to make up for the lack of testosterone produced in a body.  Before you start using Andriol, you will need to confirm the diagnosis with some tests.

Many people use Andriol and other testosterone preparations to gain more muscle mass, which is not recommended because it may have serious health consequences! Sometimes testosterone preparations are abused by athletes as a doping agent.

Use during pregnancy and breastfeeding

Andriol should not be used during pregnancy and breastfeeding.

Use and Dose

It should be avoided in patients under the age of 18.

Dosage forms include Andriol 40 mg capsules. The usual dose is 80 mg (two capsules) twice a day after meal for 2-3 weeks.

Before you start using Andriol, you will need to determine the level of testosterone in your blood, in order to avoid an overdose.

Symptoms of an overdose include: weight gain, frequent erections, anxiety and others. If you are experiencing these symptoms, contact your doctor.

Use with other medicines (Interactions)

It should not be used concomitant with the following medications:

  • Blood thinners such as:
    • warfarin (Farin),
    • acenocoumarol (Sinkum 4, Sintrom),
    • nadroparin (Fraxiparine) and others. Concomitant use with these medicines increases the risk of bleeding.
  • Medicines used to treat diabetes such as insulin, metformin. Andriol increases the effect of these medicines, so it is necessary to reduce the dose of drugs used to treat diabetes.
  • Medicines used to treat epilepsy such as:
    • carbamazepine,
    • phenobarbital. These medicines may decrease the efficacy of Andriol.

Tell your doctor about all medications and herbal medicines you are taking.

Andriol side effects

Andriol may cause the following side effects:

  1. high cholesterol and high level of triglycerides in the blood,
  2. weight gain,
  3. anxiety,
  4. severe headache,
  5. dizziness,
  6. high blood pressure,
  7. nausea,
  8. vomiting,
  9. diarrhea,
  10. trouble urinating,
  11. high hemoglobin levels,
  12. cough,
  13. shortness of breath,
  14. skin,
  15. alopecia (hair loss),
  16. enlarged prostate,
  17. frequent erections,
  18. gynecomastia (breast enlargement in men),
  19. chest pain,
  20. allergy and others.

Tell your doctor if you are experiencing any side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.