Aurorix - Medicine for depression

Aurorix is a drug that contains an active substance called moclobemide. It belongs to group of medicines called MAO inhibitors that are classified as antidepressants. This medicine is used to treat depression and social phobia.


  • It must not be used in patients who are using drugs called serotonin reuptake inhibitors or have been using them in the past two weeks, These drugs are also used in the treatment of depression:
    • sertraline,
    • fluoxetine,
    • paroxetine,
    • fluvoxamine,
    • citalopram,
    • escitalopram and others.
  • Concomitant use of these medications may cause serious serotonin syndrome.
  • Use with other MAO inhibitors, such as:
    • selegiline,
    • phenelzine,
    • isocarboxazid,
    • tranylcypromine, and others, is not allowed.
  • It must not be used in patients allergic to the moclobemide.
  • Aurorix must not be used in combination with tricyclic antidepressants, such as:
    • imipramine,
    • amitriptyline and others, because serotonin syndrome may occur.
  • It must not be used in combination with a drug called dextromethorphan (an oral cough supressant, often contained in many combination cold products), because it can cause side effects!
  • When you are starting treatment, it is necessary to inform your doctor about all medications (especially other drugs used to treat depression), you are using!
  • It also must not be used in patients with pheochromocytoma (adrenal gland tumor).
  • While using this medicament, it is recommended to avoid foods containing tyramine, such as:
    • cheese,
    • wine,
    • chocolate and other foods.

Use of Aurorix during pregnancy and breastfeeding

Use of this drug is not recommended during pregnancy unless the benefit to the mother outweighs the risk to the child. Avoid breastfeeding while using Aurorix pills.

Aurorix dose

Usual dose in the treatment of depression is Aurorix 150 mg twice a day, after a meal. Dose can be reduced to the 150 mg, once a day, or can be increased to 300 mg twice a day, depending on the effect need to be achieved.

Bear in mind that it will take a long time to feel the improvement. Your doctor will regularly monitor you, to determine the dose that suits you best.

It is not recommended use of Aurorix in children.

In patients with liver damage it is recommended to use lower doses of this medicine.

Use with other medications (Interactions)

Aurorix must not be used in combination with the following drugs:

  • Other drugs used to treat depression (serotonin reuptake inhibitors and tricyclic antidepressants), such as:
    • sertraline (Asentra, Serlift, Sidata, Sonalia, Tragal, Tralin, Zoloft),
    • fluoxetine (Flunisan, Flunirin, Flusetin),
    • paroxetine (Actapax, Arketis, Seroxat),
    • citalopram (Citalex, Cipramil),
    • escitalopram (Cipralex, harp, Elicea, Eloryqa, escilopram, Esram, Estimopram, Lata),
    • amitriptyline (Triamyl),
    • clomipramine (Anafranil),
    • vortioksetin (Brintellix),
    • duloxetine (Cymbalta), and others. If you are taking some of these drugs, you will need to stop using these medicines and after 14 days you can start using Aurorix. The concomitant use of these medicines can cause serotonin syndrome:
      • irregular heartbeat,
      • high fever,
      • loss of consciousness,
      • headache,
      • high blood pressure,
      • confusion,
      • seizures and other symptoms. Serotonin syndrome can be life-threatening.
  • Dextromethorphan, a drug used to treat cough (keep in mind that dextromethorphan is contained into the numerous products used to treat colds and available OTC). Concomitant with dextromethorphan, can cause side effects on the central nervous system.
  • Drugs used in the treatment of severe pain, such as:
    • morphine,
    • fentanyl,
    • tramadol,
    • pethidine, and others. Aurorix may increase the effect of these drugs and must not be used concomitantly with these medicines!

Tell your doctor about all medications and herbal products you are using.

Aurorix side effects

It may cause the following side effects:

  • nausea,
  • vomiting,
  • hyponatremia (decrease in sodium levels in the blood),
  • diarrhea,
  • constipation,
  • flushing,
  • restlessness,
  • irritability,
  • headache,
  • dizziness,
  • dry mouth,
  • anxiety,
  • insomnia,
  • serotonin syndrome,
  • allergy and others.

Tell your doctor if you are experiencing any side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.