Berlithion - dose | use | side effects

This article was medically reviewed by M.Pharm, Marko Tanaskovic on Thu, 27 Dec 2018. To read more about an author, click here.

Berlithion medicine contains an active substance called thioctic acid. This drug works by improving the metabolism and thus reduces damage of the peripheral nerves also reducing a burning sensation in the fingers, numbness of the fingers, finger pain and others. Damage of the peripheral nerves is especially common in patients with diabetes, and it is often used in these patients to reduce nerve damage.


  • It should be avoided in patients allergic to thioctic acid or other similar drugs.
  • Since it contains thioctic acid which is similar to vitamins, this medicament very rarely causes side effects and is well tolerated by the large majority of patients.
  • It should be used with extra precautions in patients with diabetes, because it can lower your blood glucose level and thus cause hypoglycemia (low blood sugar) in these patients. It should be noted that it can very rarely cause hypoglycaemia. If you are experiencing symptoms of hypoglycemia such as:
    • headache,
    • dizziness and increased sweating, immediately contact your doctor.
  • Berlithion and alcohol should not be used in combination, because alcohol may nullify the effect of this drug.
  • Magnesium, calcium and iron preparations as well as antacids (used to treat heartburn), could also nullify the effect of this medicine. If you are using these drugs take them 8 hours after. You should use Berlithion in the morning and preparations of magnesium, calcium or iron in the evening. Considering that milk and dairy products contain large amounts of magnesium and calcium, you will need to reduce your intake of milk and dairy products while using Berlithion pills.

Use of Berlithion during pregnancy and breastfeeding

It can be used during pregnancy only if the benefit to the mother outweighs the risk to the child. Consult your doctor about the benefits and risks of using this pills during pregnancy and breastfeeding.

Berlithion use and dose

  • It should be taken on an empty stomach in the morning, half an hour before breakfast.
  • It is necessary to take pills for a long period of time (probably lifelong) to alleviate nerve damage.
  • The usual dose is Berlithion 600 mg once a day.
  • If you take more than your doctor recommended, nausea and vomiting may occur.
  • Do not stop using Berlithion abruptly, without your doctor advice.

Use with other medicines (Interactions)

It may increase the effect of medicines used to treat diabetes, and keep in mind that it may cause hypoglycemia (low blood sugar) in these patients.

There is some data showing that these pills can reduce the effects of cisplatin (drug used to treat cancer).

Berlithion side effects

This medicine may cause the following side effects:

  1. nausea,
  2. vomiting,
  3. diarrhea,
  4. abdominal pain,
  5. impaired taste,
  6. allergy and others.

Tell your doctor if you are experiencing any side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.