Betahistine - Use | Dose | Side Effects

This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.

Betahistine (Serc) is analog of substance histamine has been shown to reduce the lymphatic pressure to improve inner ear microcirculation. This pressure actually causes the symptoms such as dizziness, tinnitus, nausea and vomiting. And with that increased fluid pressure in the inner ear this medicine is beneficial for you. Betahistine (Serc) exerts a minimal effect on the secretion of gastric acid, which is the process where the role of mediators play an H2-receptors. Betahistine (Serc) is completely absorbed after oral administration and peak plasma concentrations are obtained approximately one hour after oral administration in patients who have taken it glucose. Approximately 80-90 % of the administered dose is excreted in urine in the form of a 2-pyridyl-acetic acid, wherein the maximum rate of excretion reach in an interval of 2 hours after application. Betahistine (Serc) is used when you have vertigo, tinnitus and hearing damage caused by Meniere's disease.

Warning and precautions

Warn your doctor if you are taking other medications, have a chronic disease, a metabolic disorder, you are hypersensitive to medicines or had an allergic reaction to some of them. The medicine should not be taken if you have a tumor of the adrenal gland called pheochromocytoma, if you are sensitive to any integral component of the medicine at the same time or if you are taking medicines called antihistamines. Caution is advised if you have a peptic ulcer and the occasional dyspepsia (digestive disorders or food) that occurs in patients taking betahistine (Serc). Caution is also required if you suffer from asthma. Betahistine (Serc) should be used with caution if you are prone to hives, skin rash or allergic rhinitis, due to a possible worsening of these symptoms.

Taking with food and drinks

Take betahistine (Serc) during the meals.

Pregnancy and lactation

Before you begin taking any medicine, consult your doctor or pharmacist. Caution should be exercised when prescribing the medicine to pregnant women. Betahistine (Serc) is excreted in breast milk, in concentrations that are similar to those which are registered in the plasma. Toxic effects of betahistine (Serc) in infants at these concentrations are not known. Therefore, the application of betahistine (Serc) should be avoided in patients who are breastfeeding.

Effects on ability to drive and use machines

Rarely, somnolence may occur while you are taking the medicine. If this happens, do not drive a motor vehicle or machinery.

Use with other medicines

Please note that this information may relate to the medicines that you no longer use, and the medicines that you are planning to apply in the future. Tell your doctor if you are taking or have recently applied any other medicines including medicines obtained without a prescription. There are no proven cases of dangerous interactions with other medications you are taking at the same time, but do not use betahistine (Serc) simultaneously with medications called antihistamines.

Medicines use

If you think that the medicine have too weak or too strong effect on your body, consult your doctor or pharmacist.

Adults (including elderly)

Initial oral therapy was 8 to 16 mg three times a day taken with meals. Maintenance doses are generally range from 24-48 mg per day. The dosage can be adjusted to meet the needs of individual patients.


Betahistine tablets are not recommended for use in children younger than 18 years because of the lack of data regarding its safety and efficacy. Your doctor will advise you how long you should take your medicine betahistine (Serc). Do not interrupt treatment because in this case the symptoms of your illness occur again.

Side effects

There are registered relatively few side effects. These include disorders of the gastrointestinal tract (including dyspepsia, digestive disorders of food), headache, skin rash and itching.

If you forget to take the medicine

If you forget to take medication on time, do not use double dose later. Simply continue to use the medicine according to the usual schedule. If you forget to take a dose, take the medication as soon as possible.


If you apply more than the prescribed dose is, consult your doctor or pharmacist!

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If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.

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