Bromazepam - dose | side effects | overdose

This article was medically reviewed by M.Pharm, Marko Tanaskovic on Thu, 27 Dec 2018. To read more about an author, click here.

Bromazepam medicine belongs to group of benzodiazepines and is prescribed as sedative or sleeping pill. It is used for short-term treatment of insomnia and anxiety. It should not be used for longer than 2-3 months, because it can cause physical and psychological dependence.


It should be avoided in patients allergic to bromazepam or other similar drugs:

  • Diazepam (Bensedin),
  • Nitrazepam,
  • Tetrazepam,
  • Lorazepam and alprazolam (Ksalol, Xanax).

If you are experiencing symptoms of an allergy, such as:

  • skin rash,
  • redness of the skin,
  • swelling of the face,
  • swelling of the tongue,
  • difficulty breathing

contact your doctor immediately!

It should be avoided in patients who already have breathing problems because bromazepam may further worsen breathing in these patients.

Since this drug causes muscle relaxation, it should be avoided in patients suffering from myasthenia gravis (muscle weakness).

Bromazepam should be avoided in patients with sleep apnea (short periods during sleep when breathing stops).

It should be used only with extra precautions in patients suffering from depression as well as in patients with impaired hepatic or renal function.

Bear in mind that this drug can cause physical and psychological dependence, especially if it is used in large doses over a long period of time. It should be avoided in patients who are more prone to addiction.

If you become addicted to this drug, abruptly discontinuation of the drug will result in serious side effects:

  1. chest pain (especially if pain is spreading to the hand and neck, because it can be a symptom of a heart attack),
  2. shortness of breath,
  3. cough,
  4. restlessness,
  5. irritability,
  6. hallucinations,
  7. behavior change,
  8. mood swings and other symptoms.

If these symptoms occur, immediately contact your doctor.

Keep in mind that at the beginning of treatment you may feel symptoms, such as:

  1. drowsiness,
  2. headache,
  3. dizziness,
  4. blurred vision and other symptoms.

Because these symptoms may occur, you must avoid the management of motor vehicles and machinery.

Use of Bromazepam during pregnancy and breastfeeding

Bromazepam should be avoided during pregnancy, especially during the last three months. Bromazepam can be used only if the benefit to the mother outweighs the risk to the child.

Avoid breastfeeding while using this medicine.

Bromazepam dosage

Treatment should start with the lowest dose (Bromazepam 1.5 mg once a day at bedtime). Dosage can be increased until desired effect is achieved.

In the treatment of insomnia, bromazepam should be taken half an hour before bedtime.

In the treatment of spasticity (muscle spasms), this drug should be taken as your doctor recommended. Bear in mind that bromazepam tablets may cause decreased alertness.

Do not crush or chew the tablet but swallow it whole with a glass of water.

Do not stop using this drug abruptly, because withdrawal symptoms may occur:

  1. insomnia,
  2. mood swings,
  3. fear,
  4. anxiety and others.

Dose should be gradually decreased before you may completely stop to use this drug. Example:  if you have used a dose of bromazepam 6 mg once daily, it is necessary to first reduce dose to bromazepam 3 mg once a day, after what the dose should be reduced to 1.5 mg once a day and only after that you can completely stop using this drug.

Bromazepam and alcohol should never be used in combination, because alcohol can significantly enhance the effect of this medicine! If you are using this medicine concomitant with alcohol, you can fall into a deep sleep which may be life threatening!

Use with other medicines (Interactions)

Bromazepam should be avoided in combination with the following drugs:

  • Antipsychotic drugs, used to treat psychiatric disorders.
  • Narcotic (opioid) analgesics, used in the treatment of severe pain, such as:
    • morphine,
    • tramadol (Trodon),
    • fentanyl and others. Concomitant use of these medications with Bromazepam, increases the risk of breathing problems.
  • H1 antihistamines used to treat allergy symptoms, such as:
    • dimenhydrinate,
    • diphenhydramine,
    • pheniramine,
    • chlorpheniramine,
    • promethazine, and others.
  • Anticonvulsant medicines, used to treat epilepsy.

Tell your doctor about all medications and herbal medicines you are taking.

Under no circumstances, do not take alcoholic beverages while using this medicine, because alcohol can significantly enhance the effect of this drug.

Bromazepam side effects

Bromazepam may cause the following side effects:

  • nausea,
  • vomiting,
  • diarrhea,
  • constipation,
  • headache,
  • dizziness,
  • mood changes,
  • muscle weakness,
  • hypersensitivity (over-responsiveness) to sensory stimuli (light, sound and pressure),
  • confusion,
  • insomnia,
  • hallucinations,
  • emotional problems,
  • memory impairment,
  • seizures,
  • allergy and others.

Tell your doctor if you are experiencing any side effect.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.