Carbocisteine - Use | Dose | Side Effects

This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.

Carbocisteine is a drug from the group of mucolytics. It works by reducing the concentration of mucus glycoprotein which reduces the viscosity of mucus and facilitates expectoration. Carbocisteine is effective only in the treatment of productive cough.

It exerts anti-inflammatory effect and can favorably affect the outcome in patients with chronic obstructive pulmonary disease.

Safety precautions

Carbocysteine is contraindicated in patients who have active peptic ulcer and in patients who are allergic to this drug.

It has an excellent safety profile and rarely causes side effects. It does not interact with other drugs. Therefore, this medicine is very safe, and can be used long-term, which is especially useful for chronic lung diseases.

It has no impact on the psychophysical abilities so you can drive a car or operate machinery while on Carrbocisteine therapy.

Carbocisteine, pregnancy and lactation

Although tests have shown no teratogenic effects of this drug, its use is not recommended in pregnant women, especially during the first three months of pregnancy.

In the studies, Carbocisteine had no effects on lactation, and can be used during breastfeeding if your doctor recommended.


Carbocysteine exists in various pharmaceutical forms, and various doses, as follows:

  • Carbocisteine 125 mg / 5 ml syrup
  • Carbocisteine 250 mg / 5 ml syrup
  • Carbocisteine 375 mg capsules

Recommended dosage for Carbocisteine 125 mg / 5 ml syrup

Age Recommended dose
Children aged 2-5 years 2.5 - 5 ml four times a day
Children 5-12 years 10 ml three times a day

This dosage form is not intended for children older than 12 years.

Recommended dosage for Carbocisteine 250 mg / 5 ml syrup

Age Recommended dose
Adults 15 ml three times a day

This dosage form is not intended for use in children.

Recommended dosage for Carbocisteine 375 mg capsules

The usual initial dose is two capsules three times a day (total 2,250 mg). After achieving desired effect, the dose is usually reduced to one capsule, four times a day.

The capsules should not be used in children.


There is no specific antidote for Carbocisteine poisoning.

If patient took a higher dose than recommended than gastric lavage can be applied.

The most common symptoms of an overdose include gastrointestinal disorders.

Side effects

Carbocisteine may cause the following side effects:

  • Immune system disorders (there are reported cases of anaphylactic shock in patients who have been treated with this drug)
  • Gastrointestinal bleeding

Carbocisteine has a very good safety data profile and rarely causes side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.

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