Cilamox

Cilamox - Precautions | Dosage | Interactions

Cilamox is a broad-spectrum antibiotic from the family of antibiotics known as penicillins. It is used to treat infections caused by bacteria and is not effective in treating viral colds and flu. It is also used to prevent infections after dental procedures and is often used as part of combined therapy (along with lansoprazole and clarithromycin) for the eradication of Helicobacter pylori, which occurs in patients who have gastric or duodenal ulcer.

Precautions

Cilamox is absolutely contraindicated in patients who are allergic to any antibiotic from the penicillin group (e.g. ampicillin, benzylpenicillin and phenoxymethylpenicillin) or from the group of a cephalosporin antibiotics (e.g. cephalexin, cefadroxil, cefahlor, ceftibuten, ceftriaxone and ceftazidime).

Allergic reactions occur very rarely (in less than 0.01% of patients), but can occur even if you have taken this medicine in the past and never had an allergic reaction. If you notice symptoms of an allergy (e.g. skin redness, swelling of the face, lips and tongue, hives and difficulty breathing), you should contact your physician. The most severe form of an allergic reaction can lead to anaphylactic shock, which can be fatal.

It should not be administered to patients with infectious mononucleosis because clinical trials have shown that the use of this drug in these patients causes maculopaular exanthema.

Cases of acute renal insufficiency induced by using this medicinal product have been reported, and for this reason use of this drug must be avoided in patients with impaired renal function.

Cilamox, pregnancy and lactation

AU TGA classified this drug in the group A - group of drugs that did not shown any kind of toxicity when administered during pregnancy. Some experts believe that this antibiotic (amoxicillin) is one of the safest for use during pregnancy.

It can be used during breastfeeding with increased caution, since it can cause allergic reactions in infants.

Dosage

Cilamox exists in the form of capsules at a dose of 250 and 500 mg and in the form of an oral suspension at a dose of 250 mg / 5 ml.

Recommended dosage for adult patients is given in the table below:

Infection Dosage instructions
Gonorrhea 500 mg every four hours
Eradication of Helicobacter Pylori 500 mg every twelve hours
Urinary infections Two doses of 3000 mg (six 500 mg-capsules). The interval between two doses should be 10-12 hours.
Severe pulmonary infections 3000 mg every twelve hours
Mild forms of respiratory infections 500 mg every eight hours
Prevention of infections after dental procedures 1000 mg every twelve hours

Swallow the capsules whole with plenty of fluid one hour before or two hours after a meal.

Children who cannot swallow the capsules should use Cilamox oral suspension.

Interactions

Cilamox should not be administered concurrently with the following drugs:

  • Probenecid and allopurinol (drugs used for the treatment of gout)
  • Blood thinners (e.g. warfarin)
  • Oral contraceptives (use another method of contraception while taking this drug).

Side effects

Cilamox may cause the following side effects:

  • Colitis (inflammation of the lining of the intestine which is characterized by severe diarrhea)
  • Flu-like symptoms (fever, chills, sore throat, cough, and others)
  • Seizures
  • Change in the tongue color
  • Oral and vaginal candidiasis
  • Shortness of breath
  • Anemia
  • Difficulty urinating
  • Hyperactivity
  • Allergic reaction

References

  1. NCBI link
  2. PIL