Concor - 2.5mg | 5mg | 10mg - Use | Effects

This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.

Concor is a medicine that contains an active substance called bisoprolol. It belongs to group of beta blockers. It is used in the treatment of hypertension and angina pectoris.


Concor should be avoided in patients allergic to the active substance bisoprolol or other similar medications, such as:

  • metoprolol,
  • atenolol,
  • carvedilol,
  • nebivolol and others.

If you are experiencing symptoms of an allergy, such as:

  • skin rash,
  • itching of the skin
  • swelling of the face,
  • swelling of the lips,
  • swelling of the tongue,
  • difficulty breathing,

doscontinue use and call your doctor.

Concor 5 mg should be avoided in patients with slow heart rate (bradycardia) or atrioventricular block (AV) II or III degree. This medicine may slow the heart rate in these patients and cause serios complications.

It should be avoided in who have cardiogenic shock or low blood pressure (less than 90 mmHg). Use of this medicine in such patients will make condition worse.

Concor can cause constriction of the bronchi, therefore should be avoided in patients with asthma because it may trigger an asthma attack.

This medicine should be avoided in patients with adrenal gland tumor (pheochromocytoma).

This medicine may hide the signs of low blood sugar (such is rapid heartbeat), therefore should be used only with extra precautions in patients with diabetes.

Concor 5 mg should be used with extra precautions in the following conditions:

  • Heart failure
  • In patients with Prinzmetal's angina
  • Thyroid gland disorders
  • Hepatic impairment
  • In patients with renal impairment

If you are planning a surgery, inform your doctor that you are taking this medicine.

Use during pregnancy and breastfeeding

Concor may be used during pregnancy only if the benefit to the mother outweighs the risk to the child. According to the US Agency for Food and Drug Administration (FDA), this medicine belongs to the group C. This means that animal studies have shown adverse effects on the fetus, but there are no human studies.

It is not known whether this medicine passes into breast milk. Avoid breastfeeding while using this medicine.

Use and Dose

Dosage forms include: Concor 2.5 mg, Concor 5 mg and Concor 10 mg.

Therapy should start with low dose and then gradually increased to a regular maintenance dose.

  • In the treatment of mild hypertension, the recommended dose of  Concor is 2.5 mg taken once a day.
  • In the treatment of severe hypertension, the recommended dose of Concor is 5 mg or 10 mg taken once a day. The maximum daily dose is 20 mg!
  • In the treatment of angina pectoris, the usual dose is 5 mg taken once a day.

Concor 5 mg should be taken in the morning during or after breakfast. Swallow the tablet whole with a glass of water. Do not chew the tablets because it can affect this medicine.

It is necessary to reduce the dose gradually before stopping this medicine. Always talk to your doctor about the safest way to gradually reduce your medicine.

Use with other medicines (Interactions)

Concor should be avoided in combination with the following medicines:

  • Medicines used in the treatment of heart diseases, the so-called calcium antagonists, such as:
    • verapamil,
    • diltiazem and others. These medicine can slow the heart rate as well as Concor 5 mg, and may cause serious side effects.
  • Other medicines used in the treatment of high blood pressure, such as:
    • methyl dopa,
    • moxonidine,
    • clonidine and others. Concomitant use with these medicines may lead to worsening of the symptoms of heart failure.
  • Antiarrhythmics, medicines used in the treatment of heart disorders (arrhythmia), such as:
    • flecainide,
    • disopyramide,
    • lidocaine,
    • quinidine,
    • amiodarone and others.
  • Other beta blockers, even in the form of eye drops, such as:
    • betaxolol,
    • timolol and others. These medicines can be absorbed into the blood and may increase some of the side effects.
  • Digoxin, a drug used in the treatment of heart failure.
  • Antidepressants, medicines used in the treatment of depression, such as:
    • imipramine,
    • desipramine,
    • amitriptyline,
    • nortriptyline,
    • moclobemide,
    • phenelzine,
    • selegiline,
    • isocarboxazid and others. Concomitant use of Concor with these medicines, can lead to hypotension (low blood pressure).

Tell your doctor about all medications and herbal products you are taking.

Concor Side effects

Concor 5 mg can cause the following side effects:

  1. nausea,
  2. vomiting,
  3. diarrhea,
  4. constipation,
  5. headache,
  6. dizziness,
  7. fatigue,
  8. slow heart rate (bradycardia),
  9. low blood pressure (hypotension),
  10. syncope (fainting),
  11. hearing disorders,
  12. conjunctivitis,
  13. asthma attack in patients with asthma,
  14. alopecia (hair loss),
  15. muscle weakness,
  16. numbness in hands and feet,
  17. impotence,
  18. depression,
  19. hallucinations,
  20. insomnia,
  21. nightmares,
  22. dry mouth,
  23. allergy and others.

Tell your doctor if you are experiencing any side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.

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