Controloc - Use | Dose | Side Effects
Category Proton pump inhibitors (PPIS)
Controloc is a medicine that contains an active substance called pantoprazole. It belongs to a group of medicines called proton pump inhibitors (PPIs). It works by binding to the proton pump and reducing the amount of gastric acid that is pumped into the lumen of stomach. It is used for the following conditions:
- Treatment of gastroesophageal reflux disease (GERD).
- Prevention of gastric or duodenal ulcers associated with long-term take non-steroidal anti-inflammatory drug therapy. Non-steroidal anti-inflammatory drugs are medicines used to treat pain and inflammation, such as:
- ibuprofen (Nurofen),
- meloxicam and the others. These medicines increase the risk for ulcers, therefore Controloc should be taken as a preventive measure.
- Treatment for gastric and duodenal ulcers.
- Eradication of H. Pylori in patients with gastric or duodenal ulcers in combination with antibiotics. H. Pylori is a bacteria that accompanies ulcers.
- Treatment of inflammation of the esophagus, caused by acid reflux from the stomach into the mouth, the so-called reflux esophagitis.
- Treatment of Zollinger-Ellison syndrome.
Controloc should be avoided in the following situations:
- If you are allergic to the active ingredient (pantoprazole) or other similar medicines, such as:
- rabeprazole, and others.
Controloc can be used only with extra precautions in the following conditions:
- If you have hepatic impairment.
- If you have vitamin B12 deficiency and anemia. This medicine may reduce the intestinal absorption of vitamin B12.
- If you are using medications for the treatment of AIDS (HIV).
- If you have low levels of magnesium in the blood (hypomagnesaemia). This medicine can lower magnesium levels and cause following symptoms:
- muscle cramps,
- delirium (hallucinations, confusion) and others. If you are experiencing any of these side effects, discontinue use and call your doctor.
- If you have weak bones or any bone disease. This medicine may increase the risk of bone fractures, especially in the elderly and in postmenopausal women. Long-term use (more than a year), increase the risk of bone fractures.
The drug can boost the number of bacteria in the gastrointestinal tract and cause various infections.
Call your doctor right away if you are experiencing any of the following symptoms:
- persistent vomiting,
- vomiting blood,
- weight loss,
- blood in the stool (dark-colored stools),
- difficulty swallowing,
- nausea and others.
Use of Controloc during pregnancy and breastfeeding
Controloc should not be used during pregnancy. Talk with your doctor about the risks and benefits of Controloc use during pregnancy.
This medicine passes into breast milk. therefore breastfeeding should be avoided while using this medicine.
How to use
Recommended dosage for patients above the age of 12:
|Condition||How to use|
|Gastric (peptic) and dudodenal ulcer||The usual dose is 40 mg once a day, in the morning, an hour before breakfast. The dose may be increased to 40 mg two times a day. The treatment of gastric ulcer usually lasts 4-8 weeks while treatment of duodenal ulcer lasts 2-4 weeks.|
|Eradication of H. Pylori in patients with gastric or duodenal ulcers||The usual dose is 40 mg twice a day (an hour before breakfast and an hour before dinner).|
|Zollinger-Ellison syndrome||The usual dose is 80 mg per day (two tablets of Controloc 40 mg), in the morning, an hour before breakfast.|
|Reflux esophagitis||The usual dose is 40 mg once a day in the morning an hour before breakfast. The treatment usually lasts 4-8 weeks.|
Controloc should be avoided in children under the age of 12.
A daily dose of Controloc 20 mg should not be exceeded in patients with hepatic impairment.
It shoould be taken an hour before food.
Use with other medicines (Interactions)
Controloc should be avoided in combination with the following medicines:
- Medicines used in the treatment of AIDS (HIV), such as atazanavir. Controloc can reduce the absorption of this medicine, decreasing its effects.
- Medicines used to treat fungal infections, such as:
- ketoconazole and itraconazole. Controloc reduces the absorption of these medicines, decreasing their effects.
- Medicines used in the treatment of thrombosis (known as blood thinners), such as:
- warfarin (Farin),
- acenocoumarol (Sinkum 4, Sintrom 4), and others. Concomitant use of Controloc with these medicine increase the risk of bleeding.
Tell your doctor about all medications and herbal products you are taking.
Controloc may cause the following side effects:
- blood in the stool,
- abdominal pain,
- dry mouth,
- delirium (hallucinations, confusion),
- weight loss,
- gynecomastia (enlargement of the male breast),
- low levels of sodium in the blood,
- low level of magnesium in the blood (hypomagnesaemia),
- muscle pain,
- joint pain,
- low blood platelet count (known as thrombocytopenia),
- low white blood cells count (agranulocytosis),
- high blood cholesterol,
- blurred vision,
- Stevens-Johnson syndrome,
- impaired taste,
- liver damage,
- jaundice - yellow skin and eye,
- allergy and others.
Tell your doctor if you are experiencing any of abovementioned side effects.