Coreg - Use | Dosage | Interactions | Side Effects

This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.

Coreg is a drug that contains active substance called carvedilol. It is classified into group of medicines known as beta blockers. It blocks following receptors:

  • Beta 1 adrenoceptors
  • Beta 2 adrenoceptors
  • Alpha 1 adrenoceptors

Blocking of these receptors, causes following effects:

  • Widening of blood vessels
  • Heart pumps blood more easily
  • Improving blood flow throughout the body

Coreg is used to treat following conditions:

  • Heart failure
  • Cororanay heart disease
  • Hypertension
  • Angina pectoris

Use of Coreg during pregnancy and breastfeeding

Safety of its use during pregnancy has not been confirmed, because there are no enough reliable data. It should be avoided during pregnancy, unless your doctor says you to take it.

This drug is probably excreted in breast milk, therefore you should avoid breastfeeding while using Coreg.


Coreg should be avoided if you have any of the following conditions:

  • Atrioventricular block (second or third degree)
  • If your chest pain occurs at rest
  • Respiratory tract disorders (asthma and bronchitis)
  • Diabetes (type 1 or type 2)
  • Peripheral vascular disease
  • Irregular heartbeat
  • Severe liver problems
  • Breathing problems
  • Low blood sugar
  • Glaucoma
  • If you are going to have a surgery

Concomitant use with alcoholic beverages is strictly prohibited.

How to use

Recommended Coreg dosage for adults:

Condition Recommended initial dose Recommended maintenance dose
Angina pectoris 6.25 mg every 12 hours 6.25 - 25 mg every 12 hours
Hypertension 6.25 mg every 12 hours 6.25 - 25 mg every 12 hours
Congestive heart failure 3.125 mg every 12 hours 6.25 mg every 12 hours

Note: Coreg is more effective and shows much less adverse effects if taken with a meal.

You can find more information on:

Use of Coreg with other medicines (Interactions)

Coreg should be avoided in combination with following medications:

  • Medications used to lower cholesterol levels, such as: atorvastatin and rosuvastatin)
  • Medication used to lower the levels stomach acid, such as: esomeprazole(brand name Nexium), omeprazole, lansoprazole and others.
  • Levothyroxine (used to treat low thyroid activity)
  • Duloxetine (used to treat anxiety and depression)
  • Valsartan (used to treat hogh blood pressure)
  • Furosemide (used to increase fluid excretion)
  • Aminophylline
  • Dyphylline
  • Terbutaline
  • Verapamil and diltiazem
  • Methyldopa
  • Formoterol
  • Methacholine

You should inform your doctor about all medications and herbal remedies you are taking.

Side effects

Coreg is usually well tolerated. However, you should know its adverse effects and you should call your doctor if you are experiencing any of the following:

  • Hyperglycemia
  • Shortness of breath
  • Chest pain
  • Weight gain
  • Bradycardia
  • Chills
  • Flu-like symptoms (cough and fever)
  • Temporary vision loss
  • Anuria (decreased amount of produced urine)
  • Slurred¬†speech
  • Insomnia
  • Periodontitis
  • Melena
  • Albuminuria

Brand names: Carvil, Carvedilol, Dilatrend, Eucardic and Carloc.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.

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