Duricef - Dosage | Side Effects | Use

This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.

Duricef is a drug that contains an active substance called cefadroxil. Duricef belongs to a group of medicines called cephalosporins. Duricef is an antibiotic and have a bactericidal effect (kills bacteria). It is used for treatment of the following infections:

  • Respiratory tract infections:
    • tonsillitis,
    • laryngitis,
    • pneumonia,
    • bacterial bronchitis.
  • Middle ear infections (otitis media)
  • Gynecological infections
  • Urinary tract infections (cystitis, pyelonephritis)
  • Skin and soft tissue infections (cellulitis and other infections)


Duricef should not be used in patients who are allergic to the active substance cefadroxil and other similar drugs, such as:

  • cefpodoxime,
  • ceftazidime,
  • cefahlor (Alfacam),
  • ceftriaxone (Longacef),
  • cefprozil (Bacticef),
  • ceftibuten (Cedax),
  • cephalexin (Palitrex),
  • cefixime (Cefapan),
  • cefazolin,
  • cefepime (Cefim),
  • cefotaxime,
  • cefprozil (Cefzil),
  • penicillins,
  • ampicillin,
  • amoxicillin and others. If you are experiencing symptoms of an allergy, such as:
    • skin rash,
    • itching,
    • redness,
    • swelling of the face,
    • tongue swelling,
    • difficulty breathing, contact your doctor immediately.

This medicine should be avoided or may be used only with extra precautions in patients who have or have ever had an intestinal infection called colitis. Duricef, like all other antibiotics may disturb the gut flora and cause intestinal infections. If you are experiencing diarrhea (especially if the diarrhea is presented with the blood), contact your doctor immediately.

It should be used only with extra precautions in patients with kidney disorders.

Use of Duricef during pregnancy and breasfeeding

According to the US Agency for Food and Drug Administration, Duricef belongs to group B (FDA: Group B), which means that animal studies have shown safety of Duricef use during pregnancy, but there are no studies on humans.

Duricef passes into breast milk, therefore it is recommended to avoid breastfeeding while using Duricef capsules. Instead of breast milk, you can give your baby formula milk.

How to use

It should be taken regardless of food, with a glass of water.

Patients above the age of 12:

Condition Dose
Inflammation of the tonsils (tonsillitis) 500 mg - 1000 mg, once or twice a day, depending on the severity of the infection. Treatment should last for 7-10 days
Skin and soft tissue infection 1000 mg, once a day
Inflammation of the pharynx (pharyngitis) 500 mg -1000 mg, once or twice a day, depending on the severity of the infection, during the 7-10 days
Urinary tract infections 1000 mg, twice a day (na 12 sati), during two weeks

In children under the age of 12, the dose of Duricef should be calculated according to child's body weight (usually about 30 mg / kg). In children, it should be used as syrup.

You need to use Duricef capsule / syrup, for as long as recommended by doctor, even if you feel better. Last of the treatment is important to eliminate all bacteria and completely eliminate the cause of infection.

Duricef is found in the form of capsules and syrup.

Use with other medicines (Interactions)

There are no known interactions of Duricef with other medications or food. It is only known that Duricef may affect the results of certain lab tests (Coombs test, glucose in the urine, and others).

Tell your doctor about all medications and herbal products you are taking.

Side effects

Duricef may cause the following side effects:

  1. nausea,
  2. vomiting,
  3. diarrhea,
  4. disturbed digestion,
  5. headache,
  6. dizziness,
  7. infections (genital candidiasis, colitis),
  8. reducing the number of leukocytes in the blood (leucopenia),
  9. joint pain,
  10. flu-like symptoms (fever, sore throat),
  11. liver damage accompanied by jaundice (yellowing of the skin and eye),
  12. irritation,
  13. allergy (rash, itching, swelling of the face, tongue swelling, difficulty breathing) and others.

Immediately tell your doctor if you are experiencing any side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.

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