Etodin Fort - Pregnancy | Dosage | Side Effects
Etodin Fort is a drug used for the treatment of osteoarthritis and rheumatoid arthritis to ease acute and chronic pain that accompanies these conditions. It also helps to relieve other arthritis symptoms, such as: swelling, stiffness and inflammation. As the active substance contains etodolac, a novel drug from the group of non-steroidal anti-inflammatory drugs.
When this drug should not be used
- If you have bleeding
- If you have liver damage
- If you have congestive heart failure or have recently had a heart attack
- If you have high blood pressure
- If you have asthma
- If you have an ulcer or have ever had a gastrointestinal bleeding
- In pregnant women (in the last trimester)
This drug should be administered with caution in patients with a history of asthma or other respiratory disorders, bearing in mind that Etodin Fort can cause bronchospasm.
Patients who have kidney damage or take medicines that can damage the kidney (such as diuretics) should cautiously take Etodin Fort as it causes a dose-dependent reduction in the production of prostaglandins, which accelerates the kidney failure.
It is necessary to regularly monitor liver and kidney function while you are on Etodin Fort treatment.
This medication increases the risk of heart attack and must be used with caution in patients who have atherosclerosis, high cholesterol, hypertension, or other risk factors for heart attack.
Very rarely, Etodin Fort can cause toxic epidermal necrolysis and Stevens-Johnson syndrome, which in rare cases, can have a fatal outcome.
Etodin Fort may negatively affect the fertility of women, and should be avoided in women trying to conceive.
To reduce the risk of side effects to a minimum, it is necessary to use the lowest possible dose and treatment should last as short as possible. This medication can be purchased only with a prescription, and the doctor will determine the exact dose and duration of treatment.
Etodin Fort during pregnancy - yes or no?
Etodin Fort should not be used during pregnancy, especially during the last trimester, because its application in the last trimester causes premature closure of the ductus arteriosus and can cause cardiovascular complications in babies.
There is not enough data on Etodin Fort safety during breastfeeding, which is why it should be avoided.
The recommended dose is 200 mg or 300 mg twice daily during meal or immediately after a meal.
It should not be used in children.
The elderly are at greater risk of side effects, and the application should be limited in such patients.
Etodin Fort interactions
Drugs that should not be used concurrently with Etodin Fort and the reasons why are given in the table below:
|Drugs||Reason why these drugs should not be used in combination with Etodin Fort|
|Antuhypertensives||Reduced antihypertensive effects|
|Diuretics||Reduced diuretic effect|
|Cardiotonic glycosides||Increasing glycoside blood levels which lead to adverse effects|
|Lithium||Increasing lithium blood levels which increases risk of unwanted effects|
|Cyclosporine||Increased risk of nephrotoxicity|
|Corticosteroids||Increased risk of bleeding in digestive tract|
Etodin Fort and its side effects
Etodin Fort may cause the following unwanted (adverse) effects:
- Aplastic anemia
- Hemolytic anemia
- Allergic reactions including anaphylaxis
- Shortness of breath due to bronchospasm
- Toxic epidermal necrolysis and Stevens-Johnson syndrome
- Changes in mood (depression, anxiety, etc.)
- Abnormal vision
- Optical neuritis
- Bleeding in the digestive tract
- Interstitial nephritis