Ferro-f-tab - Dosage | Interactions | Effects
This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.
Ferro-f-tab is a drug containing two active substances (310 mg of ferrous fumarate and 310 micrograms of folic acid). It is used for the prevention and treatment of anemia caused by iron and vitamin B9 (folic acid) deficiency.
Ferro-f-tab should not be used in patients who are allergic to iron or folic acid.
Before starting this drug, it is important to determine the exact cause of anemia. This medicine will not work in case of megaloblastic anemia caused by a deficiency of vitamin B12.
Before you start treatment, it is necessary to inform your doctor if you are receiving or have recently received blood transfusions.
The use of this drug in patients who have an active ulcer in the stomach or duodenum is contraindicated.
Tell your doctor if you have any of the following conditions:
- Hemolytic anemia.
Do not exceed the dose recommended by your doctor, because an iron overdose may have a fatal outcome! Overdose is particularly fatal in children. Symptoms of an iron overdose include: coughing up blood, vomiting blood, severe abdominal pain, pale skin, blue lips, weak and rapid pulse as well as difficulty breathing. If you notice any of these symptoms, you should contact your doctor immediately.
Patients who have undergone partial gastrectomy (removing part of the stomach) should not use this medicine.
The use of Ferro-f-tab in patients with folate-dependent carcinoma is contraindicated, as this may aggravate the patient's medical condition.
Ferro-f-tab often causes black and tarry stools as an adverse reaction, but this has no clinical significance.
It should not be used in children under the age of 12.
Ferro-f-tab, Pregnancy and Breastfeeding
Ferro-f-tab is a mineral-vitamin preparation and can be used during pregnancy if directed by your doctor.
The usual dose for prevention of anemia is one tablet (one tablet contains 310 mg of ferrous fumarate and 350 micrograms of folic acid) daily.
The usual dose for treatment of anemia is 1-2 tablets a day. Never take more tablets than directed by your doctor.
It is best to take the tablet on an empty stomach, in the morning, immediately after waking up, because food reduces absorption of iron in the body.
In order to improve iron absorption, it is recommended to take vitamin C or a glass of lemon juice together with the tablet.
Sometimes, due to stomach upset, this medication must be taken between meals. In this case, it is recommended to take a tablet with at least 250 ml (8 fl. oz.) of water and do not lie down for 30 minutes after taking the pill.
Dose adjustment is required if taken with food.
Ferro-f tab may interfere with the absorption of antibiotics, such as:
For this reason, these antibiotics must be taken at least two hours before or after taking the Ferro-f tab.
Ferro-f-tab should not be used at the same time with any of the following drugs:
- Antacids (e.g. hydrotalcite, magnesium hydroxide, aluminum hydroxide, calcium carbonate, aluminum carbonate, bismuth subsalicylate, sodium hydrogen carbonate and others).
- Drugs used to treat tuberculosis.
- Oral contraceptives (e.g. levonorgestrel / ethinyl estradiol, mestranol / norethindrone, norethindrone / ethinyl estradiol, norgestrel / ethinyl estradiol and others).
- Dolutegravir (medication used to treat HIV). Ferro-f-tab interferes with the absorption of this drug, which reduces its effectiveness in treating HIV. Ferro-f tab should be taken at least 6 hours before or after taking dolutegravir.
- Fluorouracil (medication used to treat various types of cancers). Since the Ferro-f tab contains folic acid, it can increase the effects of fluorouracil, which increases the risk of side effects (anemia, diarrhea, nausea, nerve damage, bleeding, and others).
- Capecitabine (medication used to treat gastric cancer, breast cancer and colorectal cancer). Ferro-f-tab may increase the effect of capecitabine, which increases the risk of side effects.
- Dimercaprol (medication used to treat acute poisoning with heavy metals). Dimercaprol can create a complex with iron that is toxic to the body, and simultaneous use must be avoided.
- Sulfasalazine (medication used to treat ulcerative colitis).
- Pyrimethamine (medication used to treat malaria).
- Methotrexate (medication used to treat cancer).
- Potassium-sparing diuretics (e.g. triamterene).
- Methyldopa (medication used to treat hypertension).
- Levodopa (medication used to treat Parkinson's disease).
Alcohol may reduce the effectiveness of this medicine and simultaneous use with alcoholic beverages must be avoided.
Possible side effects include:
- Black stool (occurs very often).
- Presence of blood in the stool.
- Sharp and severe stomach pain.
- Allergic reactions (tightness in the chest, difficulty breathing, swelling of the face, tongue, throat and mouth).
- Difficulty swallowing.
- Sore throat.
- Leg pain.
- Dark urine.
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If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.