Finpros - Interactions | Overdose | Side Effects
Finpros contains the active substance known as finasteride. It is a competitive inhibitor of the 5-alpha reductase type II, an enzyme which is responsible for converting testosterone into dihydrotestosterone (DHT). Since benign prostatic hyperplasia (BPH) depends on the conversion of testosterone to DHT, Finpros is used to relieve symptoms of benign prostatic hyperplasia.
In clinical trials, Finpros (finasteride) has reduced the incidence of urinary retention from 7% to 3% during the four years of application. Also, the need for surgical intervention in BHP patients was also reduced.
Also, this drug reduces the risk of progression of BHP and reduces the risk of its complications.
When caution should be exercised?
The only absolute contraindication for the use of this drug is an allergy to finasteride or other Finpros ingredients.
This medicine is intended only for men and must never be administered in women and children!
Finpros affects the level of prostate specific antigen (which is used in the diagnosis of prostate cancer), and can make diagnosis of prostate cancer difficult. In studies that have been conducted with this drug, an increased incidence of prostate cancer in patients taking this medicine was not established.
Few cases of breast cancer in men taking this drug were reported, and it is necessary to contact your doctor if you notice any changes in your breast.
How should you take Finpros?
The recommended dose is 5 mg (one tablet of Finpros) a day. Commonly, this drug is combined with doxazosin - a drug that is also used to relieve the symptoms of BPH.
This medication leads to improvement of symptoms very quickly. Doctors usually recommend that therapy last 6 months to assess the effectiveness of therapy.
It can be taken with a meal or between meals.
There is no need to reduce the dose in geriatric patients.
To date, there are no reported cases of Finpros overdose, although there are studies in which patients took 80 mg per day but no side effects were reported.
However, never exceed the dose that your doctor prescribed.
So far, no clinically significant interactions have been identified, although this medicine is metabolized via the enzyme CYP3A4 (this enzyme is responsible for metabolism of 50% of all drugs). Co-administration with other medications usually leads to a slight increase in the blood concentration of Finpros, but it does not cause unwanted effects, and therefore these interactions have no significance.
Thus, for example, diltiazem (a drug used in cardiac diseases) increases the level of Finpros in the blood, but this interaction usually has no clinical significance. It is only recommended to monitor patients more frequently and possibly to reduce a dose of Finpros in patients taking dilitazem.
Finpros side effects
Finpros may cause the following side effects:
|Decreased volume of ejaculation||Rash||Palpitations|
|Impotence||Abnormal ejaculation||Pruritus and urticaria|
|Decreased libido||Gynecomastia||Increased liver enzymes|
|Runny nose||Increased breast tenderness||Pain in the testicles|
In addition to these side effects, other have also been reported, including:
- Runny nose, sneezing, and other flu-like symptoms
- Back pain
- Breast cancer in men (very rare cases)