Gabaton

Gabaton - Dosage | Overdose | Side Effects

Gabaton contains gabapentin - a drug used to treat epilepsy and neuropathic pain (usually in diabetic patients). How it works exactly is not known. Mostly it is combined with other drugs in the treatment of epileptic seizures.

Contraindications and precautions when applying Gabaton

Considering that almost the entire amount of drug is eliminated via the kidney, it is necessary to adjust the dose of Gabaton in patients with damaged kidneys. Patients who have kidney damage cannot properly eliminate Gabaton from the body, which is why it stays longer in the body and that can lead to an overdose. One case of gabapentin overdose in patients with renal impairment has been reported.1

Gabaton can cause acute pancreatitis, and it is essential to inform your doctor if you notice symptoms, such as:

  • Nausea
  • Long lasting pain in the stomach

Although some authors argue that this medicine can cause suicidal thoughts, the pharmacoepidemiological study conducted by R.Gibbons et al. has shown that gabapentin does not increase the risk of suicidal thoughts in patients who do not have psychiatric disorders.2 If, however, you notice unusual thoughts about harming yourself, you must immediately discontinue use and inform your doctor about it.

Gabaton, pregnancy and lactation

H.Fujii et al. compared two groups of pregnant women (one with women who took gabapentin and one with women who did not take the drug) and they determined that this drug does not increase the risk of malformations, but notes that further research is necessary.3 Your doctor will decide whether you can take this medicine while you are pregnant.

Since the infant can receive 6% of the amount of the mother's dose through breast milk, caution should be exercised during breastfeeding.

Gabaton dosage regimen

The usual dosage regimen is one capsule (300 mg) three times a day or every 8 hours. The dose can be increased if necessary.

Swallow the capsule whole with 8 ounces of water, regardless of food.

The maximum daily dose is 3600 mg.

Overdose

If you take a larger dose than you doctor recommended, then the following symptoms can occur:

  • Double vision
  • Vomiting
  • Impaired speech.

Interactions

Drugs that can increase the effects of Gabaton include:

Drugs that can decrease the efficacy of Gabaton include:

  • Antacids (aluminum and magnesium preparations)

Gabaton side effects

Gabaton may cause the following side effects:

  • Viral infections
  • Pneumonia
  • Respiratory infections
  • Urinary tract infections
  • Leukopenia
  • Increased appetite
  • Hyperkinesia
  • Somnolence
  • Ataxia
  • Nystagmus (inability to focus your eyes on one point)
  • Double vision
  • High blood pressure
  • Inflammation of the gingiva
  • Steven-Johnson syndrome
  • Breast hypertrophy
  • Chest pain
  • Arthralgia
  • Problems with teeth

Tell your doctor if you notice any of the listed side effects or if you notice any adverse effects that seem to be the result of taking Gabaton.

In clinical studies, the most commonly reported side effects are somnolence and dizziness.4

References

  1. NCBI link 1
  2. NCBI link 2
  3. NCBI link 3
  4. NCBI link 4