Gynofort vaginal cream

This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.

Gynofort vaginal cream as active ingredient contains butoconazole and is used for the treatment of fungal vulvovaginal infections caused by fungus called Candida albicans.

What precautions should you take while using Gynofort vaginal cream?

Gynofort vaginal cream should not be administered in pregnant women because there is no data on its safety and efficacy during pregnancy.

If you are allergic to butoconazole or other antifungal medicines (ketoconazole, fluconazole, and others), you should not apply this vaginal cream.

It should not be administered in girls under the age of 18.

If infection symptoms persist two weeks after applying Gynofort vaginal cream, consult a doctor to prescribe you another medicine.

If you experience unbearable irritation at the application site, you may need to stop using this cream.

Due to the presence of certain excipients, local allergic reaction may occur, but it occurs very rarely and is manifested only by mild symptoms (redness and itching at the application site).

Gynoflor contains mineral oil which may damage a condom, so you are recommended to use other contraceptive methods while using this cream.

Gynoflor, pregnancy and lactation

It should not be used during pregnancy because animal studies have shown adverse effects of this cream on the fetus.

It is not known whether it is excreted into breast milk, and it is necessary to avoid breastfeeding while using this cream.


There are no reports of an overdose with this cream.


One filled applicator (5 g of cream) applied intra-vaginally once a day at bedtime.

The treatment usually lasts from 7 to 14 days.

Interactions with other creams/drugs/food

There are no reported clinically significant interactions with other drugs. Tell your doctor if you apply some other vaginal creams or other products that are applied in the vagina.

Gynoflor side effects

The side effects of Gynoflor usually occur at the application site, and most commonly include:

  • Burning sensation at the application site
  • Increased sensitivity of the vagina
  • Pain at the application site
  • Swelling at the application site
  • Pelvic pain
  • Abdominal pain
  • Abdominal cramp
  • Vaginal inflammation

Gynoflor has a very good safety profile and does not cause serious adverse effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.

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