Helex - Medicine used for anxiety

This article was medically reviewed by M.Pharm, Marko Tanaskovic on Thu, 27 Dec 2018. To read more about an author, click here.

Helex is a medicine that belongs to the group of benzodiazepines. It reduce anxiety and fear  and cause sedation (acts as a sedative). It is used for anxiety and fear treatment.


It should not be used in the following conditions:

  • If you are allergic to Helex or other benzodiazepines such as:
    • diazepam (Bensedin),
    • lorazepam,
    • nitrazepam,
    • bromazepam and others. If you experience allergy symptoms (itching, swelling, redness), contact your doctor immediately.
  • Myasthenia gravis (severe muscle disorder). Helex may worsen myasthenia gravis.
  • If you have liver disorders.
  • If you have trouble breathing.
  • Glaucoma (increased eye pressure).

It cannot not be used in combination with alcoholic beverages, because alcohol can increase the effect of helex and cause serious side effects!

It also cannot be used for a long periods of time (no longer than 2-3 months), because it can cause addiction!

Do not stop using Helex abruptly because it may lead to withdrawal symptoms: severe headache, insomnia, agitation, irritability, muscle pain and other symptoms.

The dose should be gradually reduced for 0.5 mg every 3-4 days. For example, if you are taking 2 mg of Helex per day, then you will need to take 1.5 mg for 3-4 days, then 1 mg per day for 3-4 days and at the end 0.5 mg for 3-4 days. Then you can completely stop taking Alprazolam.

In this way, you will avoid the withdrawal syndrome.

Use during pregnancy and breast feeding

It should not be used during pregnancy and breastfeeding, unless it is necessary.

Helex is used in pregnancy only if the benefit to the mother outweighs the risk to the child.

According to the FDA, this medicine belongs to the group D (FDA: Group D), which means that Helex is harmful to the fetus.

Helex passes into breast milk and may harm your baby. Avoid breast-feeding while using Alprazolam.

How to use

The usaual dose of Helex is 0.25-0.5 mg, three times a day.Helex should be started at a low dose. The dose may be gradually increased until you reach desired effect. The maximum daily dose is 3 mg per day, in divided doses.

Take tablet with a glass of water. Do not crush the tablet, just swallow it whole.

Helex is most commonly used in the evening in higher dose than during the day (e.g. If you are taking 0.25 mg during the day, then the doctor will tells you to take 0.5 mg at the evening).

Use with other medicines (Interactions)

Helex should not be used in combination with the following medications:

  • If you are taking other medicines to treat anxiety or depression such as:
    • fluoxetine,
    • paroxetine,
    • fluvoxamine,
    • sertraline, and others.
  • If you are taking narcotic (opiate) analgesics-pain medications, such as:
    • morphine,
    • codeine,
    • tramadol, and others.
  • If you are taking medicines to treat fungal infections such as:
    • ketoconazole,
    • fluconazole,
    • itraconazole and other.
  • If you are taking medicines for heart disorders treatment such as:
    • nifedipine,
    • nicardipine,
    • amiodarone, and others.
  • If you are taking medicines for AIDS (HIV) treatment such as:
    • efavirenz,
    • nelfinavir,
    • saquinavir and others.
  • If you are taking cyclosporine, used to treat autoimmune disorders
  • If you are taking medications to treat epilepsy, such as:
    • carbamazepine,
    • valproic acid,
    • phenytoin,
    • phenobarbital and others.
  • If you are taking antibiotics such as:
    • erythromycin,
    • azithromycin,
    • clarithromycin, and others.
  • If you are taking oral contraceptives to prevent unwanted pregnancy such as:
    • Yasmin.
  • If you are taking St. John's wort.

Tell your doctor about all medications and herbal medicines you are taking because Helex may interact with many medicines.

Side effects

Helex can cause the following side effects:

  1. liver damage (which is manifested by the appearance of jaundice-yellowing of the skin and eyes),
  2. Zakathisia (feeling of inner restlessness),
  3. agitation,
  4. irritability,
  5. headaches,
  6. memory loss,
  7. hallucinations,
  8. anger,
  9. aggression,
  10. suicidal thoughts,
  11. lack of attention,
  12. impaired coordination,
  13. nausea,
  14. vomiting,
  15. diarrhea,
  16. abdominal pain,
  17. dizziness,
  18. dry mouth,
  19. impotence,
  20. blurred vision,
  21. fatigue,
  22. allergy and others.

Tell your doctor if you experience any side effect.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.