Larodopa - How to use | Side Effects

This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.

Larodopa belongs to the family of medicines used to treat Parkinson's disease. It contains an active compound called levodopa. It is rarely used alone but mostly in combination with other medicines (carbidopa or benserazide) to treat Parkinson's disease.


It should be avoided in following conditions:

  • Psychosis
  • Closed-angle glaucoma
  • Melanoma
  • Renal impairment
  • Hepatic impairment
  • Gastric or duodenal ulcers
  • If you are allergic to active compound levodopa or other similar medicines. Call your doctor right away, if you are experiencing symptoms of an allergy, such as:
    1. skin rash
    2. redness of the skin
    3. swelling of the tongue and difficulty breathing

How to use

Your doctor will prescribe a dose that best suits you. Swallow the tablet whole. Do not chew the tablet, because it may affect Larodopa.

Larodopa can be taken regardless of meals. Avoid eating high amount of foods rich in vitamin B6, such as: grains, fish, sunflower seeds, dried fruit and bananas.

Use with other medicines (Interactions)

Larodopa should be avoided in combination with following medicines:

  • Antihypertensive medicines
  • Antipsychotics, such as:
    • haloperidol,
    • benperidol,
    • fluphenazine,
    • prochlorperazine,
    • chlorpromazine,
    • trifluoroperazine and others.
  • MAO inhibitors (antidepressants), such as:
    • moclobemide,
    • selegiline,
    • phenelzine,
    • isocarboxazid and others. Concomitant use of Larodopa with these medicines may lead to hypertensive crisis.
  • Vitamin B6. Concomitant use of Larodopa and this vitamin may reduce the effects of Larodopa.

Tell your doctor about all medications and herbal products you are taking.

Side effects

Larodopa may cause following side effects:

  • Anorexia
  • Nausea
  • Vomiting
  • Tachycardia (rapid heart rate)
  • Arrhythmia
  • Postural hypotension (low blood pressure)
  • Dyskinesia (involountary muscle movements)
  • Depression
  • Anxiety
  • Insomnia
  • Confusion
  • Illusions
  • Hallucinations
  • Euphoria
  • Allergy

Call your doctor right away if you are experiencing any side effects.

Brand names: Levodopa, Dopar and L-DOPA

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.

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