Lercanidipine

Lercanidipine - Drug used to treat hypertension

Lercanidipine belongs to a group of medicines known as calcium channel blockers (also known as calcium antagonists). It causes relaxation of smooth muscles in blood vessels, thus lowering blood pressure. Therefore, this drug is used to treat hypertension (high blood pressure).

Precautions

It should be avoided in patients allergic to lercanidipine or other similar drugs, such as:

  • nifedipine,
  • nicardipine,
  • verapamil,
  • diltiazem and others.

Furthermore, it should be avoided in the following conditions:

  • In patients with heart failure
  • Patients with unstable angina pectoris
  • In patients with liver or kidney damage
  • During pregnancy as well as in the women planning pregnancy

This drug should be used in combination with alcoholic beverages, due to the higher risk of side effects.

Use during pregnancy and breastfeeding

Lercanidipine should not be used during pregnancy unless the benefit to the mother outweighs the risks to the child.

Avoid breastfeeding while using this medicine, because this medicine passes into breast milk.

How to use

The usual dose is 10 mg once a day. The best time to take Lercanidipine is 15 minutes before your meal.

The dosage can be increased to 20 mg a day until the desired effect is achieved.

It should not be given to patients under the age of 18.

It can safely be used in combination with other drugs used in the treatment of high blood pressure (ACE inhibitors and diuretics), such as:

  • enalapril,
  • captopril,
  • fosinopril (Monopril),
  • hydrochlorothiazide,
  • furosemide (Lasix),
  • spironolactone and others.

Use with other medicines (Interactions)

Lercanidipine should be avoided in combination with the following drugs:

  • Medications used in the treatment of bacterial infections (antibiotics), such as:
    • erythromycin,
    • azithromycin (Hemomycin),
    • clarithromycin, and others. These medications increase the level of Lercanidipine in the blood, thus increases the risk of side effects.
  • Medications used in the treatment of fungal infections, such as:
    • ketoconazole,
    • fluconazole,
    • voriconazole,
    • itraconazole, and others. These medications increase the level of Lercanidipine in the blood, thus increases the risk of side effects.
  • Antihistamines, used in the treatment of allergic conditions, such as:
    • terfenadine,
    • astemizole.
  • Omeprazole, a medicine used in the treatment of heartburn, stomach and duodenal ulcers as well as in eradication of Helicobacter pylori. This medicine increases the level of Lercanidipine in the blood, increasing the risk of side effects.
  • Medications used in the treatment of epilepsy, such as:
    • phenobarbital,
    • phenytoin,
    • carbamazepine and others. These medications decrease your blood levels of Lercanidipine, which can increase your risk of hypertension (high blood pressure).
  • Metoprolol (Presolol), a drug used in the treatment of high blood pressure and arrhythmias. This medicine decreases your blood levels of Lercanidipine.
  • St. John's Wort. This herb increases the level of Lercanidipine in the blood.

Avoid concomitant use of this medicine with alcoholic beverages.

Tell your doctor about all medications and herbal products you are taking.

Side effects

This drug may cause the following side effects:

  1. nausea,
  2. vomiting,
  3. dyspepsia,
  4. abdominal pain,
  5. severe headache,
  6. dizziness,
  7. rapid heartbeat (tachycardia),
  8. drowsiness,
  9. muscle pain,
  10. fatigue,
  11. allergy and others.

Tell your doctor if you are experiencing any side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.