Parvolex - Use | Side Effects | Precautions

This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.

Parvolex contains active ingredient known as Acetylcysteine. This medicine belongs to the family of medicines known as mucolytics, but it is an antidote for paracetamol poisoning, therefore it is used to treat:

  • Paracetamol overdose


Tell our doctor if:

  • You are taking other medications
  • You have a chronic disease
  • You have a metabolic disorder
  • If you are hypersensitive to any of medicines or have had allergic reactions to any of medicines.

Use of this medicine should be avoided in following conditions:

  • Asthma
  • Gastric ulcers
  • Duodenal uclers
  • Phenylketonuria

It should be used with extra precautions in elderly patients.

Use of Parvolex during pregnancy and breastfeeding

Considering that there is no experience with the use of Parvolex during pregnancy, its use during pregnancy should be avoided. Talk to your doctor before you start using this medicine during pregnancy.

It is not known whether this medicine passes into breast milk, therefore its use during breastfeeding should be avoided.

Use with other medicines (Interactions)

Parvolex should be avoided in combination with following medications:

  • Antibiotics (cephalosporins)
  • Nitroglycerin oral. Concomitant use of Parvolex and this medicine, may cause low blood pressure (hypotension) and headache.

Tell your doctor if you are taking any other medicines.

How to use

Parvolex dosage form include: concentrate for solution for infusion.

Adults and children over 14 years

Three intravenous infusion of Parvolex are used to treat paracetamol poisoning.

First infusion: Usual initial dose is 150 mg/kg of body weight infused as slow intravenous infusion during one hour.

Second infusion: Usual dose for second infusion is 50 mg/kg of body weight as slow intravenous infusion during 4 hours.

Third infusion: Usual dose for third infusion is 100 mg/kg of body weight  as slow intravenous infusion during 16 hours.

Side effects

Parvolex may cause following side effects:

  • Nausea and vomiting
  • Trouble breathing
  • Shortness of breath
  • Fever
  • Drowsiness

Tell your doctor if you are experiencing any side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.

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