Riopan - Antacid | Use | Effects | Dosage

This article was medically reviewed by M.Pharm, Marko Tanaskovic on August 12, 2018. To read more about an author, click here.

Riopan is a medicine that contains an active substance called magaldrate. It belongs to a group of medicines called antacids. It neutralizes stomach acid therefore it is used in the treatment of heartburn and to relieve symptoms of stomach or duodenal ulcers.


Riopan should be avoided in patients who are allergic to the active substance magaldrate or other similar medicines.

Riopan should be avoided in patients with ileus (a blockage of intestines caused by hypomotility of the gastrointestinal tract).

Riopan should be used only with extra precautions in the following conditions:

  • Alzheimer's disease
  • In patients with renal impairment
  • Patients with low phosphate (hypophosphatemia)
  • In patients with bone disease

This medicine should be avoided in patients under the age of 12.

Avoid prolonged use of this medicine, because it may causes bone to thin and weaken, if used long-term.

Use of Riopan during pregnancy and breastfeeding

It should be avoided during pregnancy and breastfeeding, because there are not enough clinical data available to assess its safety during pregnancy. However, if your doctor recommends you to take this medicine during pregnancy, then make sure you take it for the shortest possible time.

How to use

The usual dosage is 1 or 2 bags of Riopan, 3-4 times per day. It should be taken between meals (when symptoms of heartburn are expected). The maximum daily dose is 8 bags (6400 mg).

If your symptoms have not disappeared after 2 weeks of treatment with this medicine, talk to your doctor.

If you are experiencing worsening of symptoms (blood in the stool, black stools, severe abdominal pain), contact your doctor.

Shake well before use. You can drink this medicine undiluted or diluted with water.

Use with other medicines (Interactions)

Riopan should be used only with extra precautions in combination with the following medicines:

  • Oral anticoagulants, such as:
    • warfarin,
    • acenocoumarol.
  • Antibiotics, medicines used in the treatment of infections, such as:
    • norfloxacin,
    • ciprofloxacin,
    • ofloxacin,
    • tetracycline,
    • doxycycline, and others.
  • Isoniazid, a medicines used to treat tuberculosis.
  • Digoxin, a medicines used to treat heart failure.
  • Antipsychotic medicines, used to treat schizophrenia and other psychiatric disorders, such as: chlorpromazine.
  • Iron supplements used to treat iron deficiency.

If you are taking any of abovementioned medicines, separate Riopan dose at least 1 hour before or 2 hours after these medicines. Riopan can bind to these medicines and reduce their absorption and effects.

Tell your doctor about all medications and herbal products you are taking.

Riopan side effects

Riopan may cause the following side effects:

  1. diarrhea,
  2. loss of appetite,
  3. low phosphate levels in the blood (hypophosphatemia),
  4. which consequently causes bones to thin and weaken,
  5. dark urine,
  6. black stools,
  7. vomiting,
  8. blood in your vomit,
  9. allergy and others.

Tell your doctor if you are experiencing any side effects.

Information on this website are provided for educational purposes only and are not intended for medical advice, diagnosis or treatment.

If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.

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