Risedronate

Risedronate - Side Effects and Precautions

Risedronate belongs to the group of medicines called bisphosphonates and it is used to prevent bone fractures by preventing bone loss.

Group of bisphosphonates includes risedronate, etidronate, pamidronate, alendronate, tiludronat and zolendronat. All of these medicines slow down decomposition of hydroxyapatite crystals in bones. The mechanism of decomposition is not fully known but it is believed that biophosponate bind to bone matrix. Risedronate has at least two effects on osteoclasts (bone cells):

Risedronate belongs to the group of medicines called bisphosphonates and it is used to prevent bone fractures by preventing bone loss.

  1. Inhibits bone resorption
  2. Stimulates proliferation of osteoblasts

It is used to treat following conditions:

  • Morbus Paget
  • Postmenopausal osteoporosis
  • Hypercalcemia
  • Malignant diseases and syndromes of ectopic calcification.

Precautions

You will need to stand upright for at least 30 minutes after taking this medication. You should take it in the morning, half an hour before breakfast, with a full glass of water (at least 10 ounces).

It should be avoided in patients who are allergic to it.

It should be avoided in patients with hypocalcaemia (low calcium levels in the blood).Tell your dentist that you are taking this medicine. It should be taken only under medical supervision.

Side effects

  • Chest pain
  • Back pain
  • Pain under ribs
  • Heartburn
  • Indigestion
  • Muscle pain
  • Hip pain
  • Jaw pain
  • Numbness
  • Flu-like symptoms
  • Gastrointestinal symptoms (diarrhea, abdominal pain, constipation)
  • Headache

Call your doctor immediately if you are experiencing any of these side effects.

Brand names:Actonel and Atelvia.